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Endocrine Abstracts

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ea0020p66 | Thyroid | ECE2009

Differences in expression pattern of all-trans retinoic acid and retinoid X nuclear receptor subtypes in papillary thyroid carcinoma: a comparison with anaplastic thyroid carcinoma

Macejova Dana , Ondkova Slavomira , Galbavy Stefan , Podoba Jan , Kausitz Juraj , Brtko Julius

Retinoid receptors (RARs) upon a proper ligand binding act as all-trans retinoic acid-inducible transcription factors interacting as heterodimers with retinoid X receptors (RXRs). Predominantly, novel synthetic retinoid analogues acting through RARs as redifferentiation agents would be of great value in treating patients with advanced thyroid cancer.The objective of this study was to investigate all-trans retinoic acid/9-cis retinoic acid n...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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